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To investigate the influence of IKK2 inhibitor VIII (HY-13060, Medchem Express, Monmouth Junction, NJ) on OA advancement, MLI surgeries were being carried out in twelve-7 days-aged C57BL/6 WT mice. The mice have been injected with IKK2 inhibitor VIII (two?mg/kg, IP) just about every alternate working day for five months. OARSI scoring was carried o

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